Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

BACKGROUND: Synthetic lethal genetic interactions among proteins have been widely used to define functional relationships between proteins and pathways. However, the molecular mechanism of synthetic lethal genetic interactions is still unclear. RESULTS: In this study, we demonstrated that yeast synt...

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Bibliographic Details
Main Authors: Li, Bo, Cao, Weiguo, Zhou, Jizhong, Luo, Feng
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113237/
https://ncbi.nlm.nih.gov/pubmed/21586150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-73
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