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Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force

Carbohydrate–protein bonds interrupt the rapid flow of leukocytes in the circulation by initiation of rolling and tethering at vessel walls. The cell surface carbohydrate ligands are glycosylated proteins like the mucin P-selectin glycoprotein ligand-1 (PSGL-1), which bind ubiquitously to the family...

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Bibliografiske detaljer
Main Authors: Evans, Evan, Leung, Andrew, Hammer, Dan, Simon, Scott
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC31130/
https://ncbi.nlm.nih.gov/pubmed/11274395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061324998
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