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Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force
Carbohydrate–protein bonds interrupt the rapid flow of leukocytes in the circulation by initiation of rolling and tethering at vessel walls. The cell surface carbohydrate ligands are glycosylated proteins like the mucin P-selectin glycoprotein ligand-1 (PSGL-1), which bind ubiquitously to the family...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31130/ https://ncbi.nlm.nih.gov/pubmed/11274395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061324998 |
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