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Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond

Many biomolecular bonds exhibit a mechanical strength that increases in proportion to the logarithm of the rate of force application. Consistent with exponential decrease in bond lifetime under rising force, this kinetically limited failure reflects dissociation along a single thermodynamic pathway...

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Detalhes bibliográficos
Main Authors: Evans, Evan, Leung, Andrew, Heinrich, Volkmar, Zhu, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC509195/
https://ncbi.nlm.nih.gov/pubmed/15277675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401870101
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