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Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force

Carbohydrate–protein bonds interrupt the rapid flow of leukocytes in the circulation by initiation of rolling and tethering at vessel walls. The cell surface carbohydrate ligands are glycosylated proteins like the mucin P-selectin glycoprotein ligand-1 (PSGL-1), which bind ubiquitously to the family...

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Detalles Bibliográficos
Main Authors: Evans, Evan, Leung, Andrew, Hammer, Dan, Simon, Scott
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC31130/
https://ncbi.nlm.nih.gov/pubmed/11274395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061324998
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