Both CD4(+) FoxP3(+) and CD4(+) FoxP3(−) T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro

Cytotoxic CD4(+) T cells have been found in patients with chronic lymphocytic leukaemia (CLL) and seem to be involved in the regulation of malignant B cells. The CD4(+) T regulatory cells (Tregs) can regulate various immune cells, including B cells, by inducing their apoptosis. Hence, different subg...

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Detalhes bibliográficos
Main Authors: Lindqvist, Camilla A, Christiansson, Lisa H, Thörn, Ingrid, Mangsbo, Sara, Paul-Wetterberg, Gabriella, Sundström, Christer, Tötterman, Thomas H, Simonsson, Bengt, Enblad, Gunilla, Frisk, Per, Olsson-Strömberg, Ulla, Loskog, Angelica SI
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112339/
https://ncbi.nlm.nih.gov/pubmed/21463298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03439.x
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