Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(−) CD25(high) FoxP3(+) regulatory T cells

We have identified a novel interleukin (IL)-7-responsive T cell population [forkhead box P3 (FoxP3(+)) CD4(+) CD25(+) CD127(+)] that is comparably functionally suppressive to conventional FoxP3(+) CD4(+) CD25(+) regulatory T cells (T(regs)). Although IL-2 is the most critical cytokine for thymic dev...

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Autors principals: Di Caro, V, D'Anneo, A, Phillips, B, Engman, C, Harnaha, J, Lakomy, R, Styche, A, Trucco, M, Giannoukakis, N
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2011
Matèries:
Translational Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110322/
https://ncbi.nlm.nih.gov/pubmed/21413939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04334.x
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