Forkhead Box Protein 3 (FoxP3) Demethylation is Associated with Tolerance Induction in Peanut-Induced Intestinal Allergy

BACKGROUND: Regulatory T cells (Tregs) play an essential role in the maintenance of immune homeostasis in allergic diseases. OBJECTIVES: To define the mechanisms underlying induction of tolerance to peanut protein and prevention of the development of peanut allergy. METHODS: High or low doses of pea...

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Publicado no:J Allergy Clin Immunol
Main Authors: Wang, Meiqin, Yang, Ivana V., Davidson, Elizabeth J., Joetham, Anthony, Takeda, Katsuyuki, O’Connor, Brian P., Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671381/
https://ncbi.nlm.nih.gov/pubmed/28479331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.04.020
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