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Deep sequencing of the TCR‐β repertoire of human forkhead box protein 3 (FoxP3)(+) and FoxP3(–) T cells suggests that they are completely distinct and non‐overlapping

Maintenance of peripheral tolerance requires a balance between autoreactive conventional T cells (T(conv)) and thymically derived forkhead box protein 3 (FoxP3)(+) regulatory T cells (tT(regs)). Considerable controversy exists regarding the similarities/differences in T cell receptor (TCR) repertoir...

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Bibliografske podrobnosti
izdano v:Clin Exp Immunol
Main Authors: Golding, A., Darko, S., Wylie, W. H., Douek, D. C., Shevach, E. M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343369/
https://ncbi.nlm.nih.gov/pubmed/27880974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12904
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