T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies

Interleukin-2 (IL-2) is one of the most studied cytokines driving T-cell proliferation, activation and survival. It binds to the IL-2 receptor consisting of three chains, the α (CD25), β and common γ (γc). The binding of the CD25 chain to IL-2 is necessary to expose high-affinity binding sites for t...

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Detalhes bibliográficos
Main Authors: Lindqvist, Camilla A, Christiansson, Lisa H, Simonsson, Bengt, Enblad, Gunilla, Olsson-Strömberg, Ulla, Loskog, Angelica S I
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996557/
https://ncbi.nlm.nih.gov/pubmed/20518821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03308.x
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