Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila is an intracellular bacterium and the causative agent of Legionnaire's pneumonia. L. pneumophila is able to c...

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Detalhes bibliográficos
Main Authors: Abdelaziz, Dalia H. A., Gavrilin, Mikhail A., Akhter, Anwari, Caution, Kyle, Kotrange, Sheetal, Khweek, Arwa Abu, Abdulrahman, Basant A., Hassan, Zeinab A., El-Sharkawi, Fathia Z., Bedi, Simranjit S., Ladner, Katherine, Gonzalez-Mejia, M. Elba, Doseff, Andrea I., Mostafa, Mahmoud, Kanneganti, Thirumala-Devi, Guttridge, Dennis, Marsh, Clay B., Wewers, Mark D., Amer, Amal O.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112328/
https://ncbi.nlm.nih.gov/pubmed/21713115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00018
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