Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1β production in macrophages

Burkholderia cenocepacia infections in CF patients involve heightened inflammation, fatal sepsis, and high antibiotic resistance. Proinflammatory IL-1β secretion is important in airway inflammation and tissue damage. However, little is known about this pathway in macrophages upon B. cenocepacia infe...

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Détails bibliographiques
Auteurs principaux: Kotrange, Sheetal, Kopp, Benjamin, Akhter, Anwari, Abdelaziz, Dalia, Abu Khweek, Arwa, Caution, Kyle, Abdulrahman, Basant, Wewers, Mark D., McCoy, Karen, Marsh, Clay, Loutet, Slade A., Ortega, Ximena, Valvano, Miguel A., Amer, Amal O.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2011
Sujets:
Host Defense & Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040464/
https://ncbi.nlm.nih.gov/pubmed/21178113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0910513
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