Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis

Cystic fibrosis (CF) is the most common inherited lethal disease in Caucasians which results in multiorgan dysfunction. However, 85% of the deaths are due to pulmonary infections. Infection by Burkholderia cenocepacia (B. cepacia) is a particularly lethal threat to CF patients because it causes seve...

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Detalhes bibliográficos
Main Authors: Abdulrahman, Basant A, Khweek, Arwa Abu, Akhter, Anwari, Caution, Kyle, Kotrange, Sheetal, Abdelaziz, Dalia HA, Newland, Christie, Rosales-Reyes, Roberto, Kopp, Benjamin, McCoy, Karen, Montione, Richard, Schlesinger, Larry S, Gavrilin, Mikhail A, Wewers, Mark D, Valvano, Miguel A, Amer, Amal O
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359483/
https://ncbi.nlm.nih.gov/pubmed/21997369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.17660
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