Apoptosis-associated Speck-like Protein (ASC) Controls Legionella pneumophila Infection in Human Monocytes

The ability of Legionella pneumophila to cause pneumonia is determined by its capability to evade the immune system and grow within human monocytes and their derived macrophages. Human monocytes efficiently activate caspase-1 in response to Salmonella but not to L. pneumophila. The molecular mechani...

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Detalhes bibliográficos
Main Authors: Abdelaziz, Dalia H., Gavrilin, Mikhail A., Akhter, Anwari, Caution, Kyle, Kotrange, Sheetal, Khweek, Arwa Abu, Abdulrahman, Basant A., Grandhi, Jaykumar, Hassan, Zeinab A., Marsh, Clay, Wewers, Mark D., Amer, Amal O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030324/
https://ncbi.nlm.nih.gov/pubmed/21097506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197681
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