PI3K Pathway Mutations and PTEN Levels in Primary and Metastatic Breast Cancer

The purpose of this work was to determine whether there are differences in PIK3CA mutation status and PTEN protein expression between primary and matched metastatic breast tumors as this could influence patient management. Fifty-micron paraffin sections were used for DNA extraction and 3-micron slid...

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Detalhes bibliográficos
Main Authors: Gonzalez-Angulo, Ana M., Ferrer-Lozano, Jaime, Stemke-Hale, Katherine, Sahin, Aysegul, Liu, Shuying, Barrera, Juan A., Burgues, Octavio, Lluch, Ana M., Chen, Huiqin, Hortobagyi, Gabriel N., Mills, Gordon B., Meric-Bernstam, Funda
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112276/
https://ncbi.nlm.nih.gov/pubmed/21490305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1089
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