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Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer
PURPOSE: To investigate the incidence of germline and somatic BRCA1/2 mutations in unselected patients with triple negative breast cancer (TNBC), and determine the prognostic significance of carrying a mutation. METHODS: DNA was obtained from 77 TNBC and normal tissues. BRCA1/2 exons/flanking region...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048924/ https://ncbi.nlm.nih.gov/pubmed/21233401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2560 |
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