Earlier Age of Onset of BRCA Mutation-Related Cancers in Subsequent Generations

BACKGROUND: Women who are diagnosed with a deleterious mutation in either breast cancer (BRCA) gene have a high risk of developing breast and ovarian cancers at young ages. In this study, the authors assessed age at diagnosis in 2 generations of families with known mutations to investigate for earli...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Litton, Jennifer K., Ready, Kaylene, Chen, Huiqin, Gutierrez-Barrera, Angelica, Etzel, Carol J., Meric-Bernstam, Funda, Gonzalez-Angulo, Ana M., Le-Petross, Huong, Lu, Karen, Hortobagyi, Gabriel N., Arun, Banu K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369377/
https://ncbi.nlm.nih.gov/pubmed/21913181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26284
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