Genotype in BRCA-associated Breast Cancers

Women with BRCA1 or 2 mutations are at high risk for breast cancer. For BRCA1, a trend of increasing risk has been associated with increasing downstream (3′) location for mutations compared to the upstream (5′) mutations in the gene. For BRCA2, an increased risk of breast cancer has been associated...

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Bibliografiska uppgifter
I publikationen:Breast J
Huvudupphovsmän: Meric-Bernstam, Funda, Gutierrez-Barrera, Angelica M., Litton, Jennifer, Mellor-Crummey, Lauren, Ready, Kaylene, Gonzalez-Angulo, Ana Maria, Lu, Karen H., Hortobagyi, Gabriel N., Arun, Banu K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437798/
https://ncbi.nlm.nih.gov/pubmed/23231005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tbj.12056
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