Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer

INTRODUCTION: Translation initiation is activated in cancer through increase in eukaryotic initiation factor 4E (eIF4E), eIF4G, phosphorylated eIF4E-binding protein (p4E-BP1) and phosphorylated ribosomal protein S6 (pS6), and decreased programmed cell death protein 4 (pdcd4), a translational inhibit...

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Detalhes bibliográficos
Main Authors: Meric-Bernstam, Funda, Chen, Huiqin, Akcakanat, Argun, Do, Kim-Anh, Lluch, Ana, Hennessy, Bryan T, Hortobagyi, Gabriel N, Mills, Gordon B, Gonzalez-Angulo, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053117/
https://ncbi.nlm.nih.gov/pubmed/23102376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3343
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