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The rapamycin-regulated gene expression signature determines prognosis for breast cancer
BACKGROUND: Mammalian target of rapamycin (mTOR) is a serine/threonine kinase involved in multiple intracellular signaling pathways promoting tumor growth. mTOR is aberrantly activated in a significant portion of breast cancers and is a promising target for treatment. Rapamycin and its analogues are...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761377/ https://ncbi.nlm.nih.gov/pubmed/19778445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-75 |
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