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Cancer cells cyclically lose and regain a drug-resistant highly-tumorigenic phenotype in culture and in tumor xenografts
Drug resistance and brisk tumor initiation have traditionally been viewed as pre-existing phenotypes present in a small subpopulation of cancer cells which can expand under selective pressures. However, recent work in cancer cell lines has demonstrated that drug-resistant tumor initiating features c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3112267/ https://ncbi.nlm.nih.gov/pubmed/21518726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1120 |
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