Brain tumor stem cells maintain overall phenotype and tumorigenicity after in vitro culturing in serum-free conditions

Traditional in vitro culturing of tumor cells has been shown to induce changes so that cultures no longer represent the tumor of origin. Serum-free culturing conditions are used in a variety of cancers to propagate stem-like cells in vitro. Limited reports, however, exist on the effects of such prop...

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Bibliografiske detaljer
Main Authors: Vik-Mo, Einar Osland, Sandberg, Cecilie, Olstorn, Havard, Varghese, Mercy, Brandal, Petter, Ramm-Pettersen, Jon, Murrell, Wayne, Langmoen, Iver Arne
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018941/
https://ncbi.nlm.nih.gov/pubmed/20843775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq102
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