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Phenotypic drug profiling in droplet microfluidics for better targeting of drug-resistant tumors
Acquired drug resistance is a key factor in the failure of chemotherapy. Due to intratumoral heterogeneity, cancer cells depict variations in intracellular drug uptake and efflux at the single cell level, which may not be detectable in bulk assays. In this study we present a droplet microfluidics-ba...
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| Veröffentlicht in: | Lab Chip |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666301/ https://ncbi.nlm.nih.gov/pubmed/26456240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc00923e |
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