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Phenotypic drug profiling in droplet microfluidics for better targeting of drug-resistant tumors

Acquired drug resistance is a key factor in the failure of chemotherapy. Due to intratumoral heterogeneity, cancer cells depict variations in intracellular drug uptake and efflux at the single cell level, which may not be detectable in bulk assays. In this study we present a droplet microfluidics-ba...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Sarkar, S., Cohen, N., Sabhachandani, P., Konry, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666301/
https://ncbi.nlm.nih.gov/pubmed/26456240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc00923e
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