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Generation and Functional Assessment of 3D Multicellular Spheroids in droplet based Microfluidics Platform

Here we describe a robust, microfluidic technique to generate and analyze 3D tumor spheroids, which resembles tumor microenvironment and can be used as a more effective preclinical drug testing and screening model. Monodisperse cell-laden alginate droplets were generated in Polydimethylsiloxane (PDM...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Sabhachandani, P., Motwani, V., Cohen, N., Sarkar, S., Torchilin, V., Konry, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834071/
https://ncbi.nlm.nih.gov/pubmed/26686985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc01139f
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