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Generation and Functional Assessment of 3D Multicellular Spheroids in droplet based Microfluidics Platform
Here we describe a robust, microfluidic technique to generate and analyze 3D tumor spheroids, which resembles tumor microenvironment and can be used as a more effective preclinical drug testing and screening model. Monodisperse cell-laden alginate droplets were generated in Polydimethylsiloxane (PDM...
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| Publicado en: | Lab Chip |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834071/ https://ncbi.nlm.nih.gov/pubmed/26686985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc01139f |
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