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Phenotypic drug profiling in droplet microfluidics for better targeting of drug-resistant tumors

Acquired drug resistance is a key factor in the failure of chemotherapy. Due to intratumoral heterogeneity, cancer cells depict variations in intracellular drug uptake and efflux at the single cell level, which may not be detectable in bulk assays. In this study we present a droplet microfluidics-ba...

詳細記述

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書誌詳細
出版年:Lab Chip
主要な著者: Sarkar, S., Cohen, N., Sabhachandani, P., Konry, T.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666301/
https://ncbi.nlm.nih.gov/pubmed/26456240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5lc00923e
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