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Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors

Acting as molecular switches, all three members of the Guanosine triphosphate (GTP)-ase-family, Ras-related C3 botulinum toxin substrate (RAC), Rho, and Cdc42 contribute to various processes of oncogenic transformations in several solid tumors. We have reviewed the distribution of patterns regarding...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: De, Pradip, Rozeboom, Brett James, Aske, Jennifer Carlson, Dey, Nandini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352592/
https://ncbi.nlm.nih.gov/pubmed/32545340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061541
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