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Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine

Prasaplai is a medicinal plant mixture that is used in Thailand to treat primary dysmenorrhea, which is characterized by painful uterine contractility caused by a significant increase of prostaglandin release. Cyclooxygenase (COX) represents a key enzyme in the formation of prostaglandins. Former st...

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Detalhes bibliográficos
Main Authors: Waltenberger, Birgit, Schuster, Daniela, Paramapojn, Sompol, Gritsanapan, Wandee, Wolber, Gerhard, Rollinger, Judith M., Stuppner, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: Urban & Fischer Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111854/
https://ncbi.nlm.nih.gov/pubmed/20851587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phymed.2010.08.002
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