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Platelet gene therapy improves hemostatic function for integrin αIIbβ3-deficient dogs

Activated blood platelets mediate the primary response to vascular injury. Although molecular abnormalities of platelet proteins occur infrequently, taken collectively, an inherited platelet defect accounts for a bleeding diathesis in ≈1:20,000 individuals. One rare example of a platelet disorder, G...

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Detalhes bibliográficos
Main Authors: Fang, Juan, Jensen, Eric S., Boudreaux, Mary K., Du, Lily M., Hawkins, Troy B., Koukouritaki, Sevasti B., Cornetta, Kenneth, Wilcox, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111318/
https://ncbi.nlm.nih.gov/pubmed/21606353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016394108
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