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Platelet gene therapy improves hemostatic function for integrin αIIbβ3-deficient dogs
Activated blood platelets mediate the primary response to vascular injury. Although molecular abnormalities of platelet proteins occur infrequently, taken collectively, an inherited platelet defect accounts for a bleeding diathesis in ≈1:20,000 individuals. One rare example of a platelet disorder, G...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111318/ https://ncbi.nlm.nih.gov/pubmed/21606353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016394108 |
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