Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

BACKGROUND: The activity of the protein kinase Akt is frequently dysregulated in cancer and is an important factor in the growth and survival of tumour cells. Akt activation involves the phosphorylation of two residues: threonine 308 (Thr308) in the activation loop and serine 473 (Ser473) in the C-t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Vincent, E E, Elder, D J E, Thomas, E C, Phillips, L, Morgan, C, Pawade, J, Sohail, M, May, M T, Hetzel, M R, Tavaré, J M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111153/
https://ncbi.nlm.nih.gov/pubmed/21505451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.132
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker