14-3-3 Proteins regulate Akt Thr308 phosphorylation in intestinal epithelial cells

Akt activation has been associated with proliferation, differentiation, survival and death of epithelial cells. Phosphorylation of Thr308 of Akt by phosphoinositide-dependent kinase 1 (PDK1) is critical for optimal stimulation of its kinase activity. However, the mechanism(s) regulating this process...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Gómez-Suárez, M, Gutiérrez-Martínez, I Z, Hernández-Trejo, J A, Hernández-Ruiz, M, Suárez-Pérez, D, Candelario, A, Kamekura, R, Medina-Contreras, O, Schnoor, M, Ortiz-Navarrete, V, Villegas-Sepúlveda, N, Parkos, C, Nusrat, A, Nava, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987727/
https://ncbi.nlm.nih.gov/pubmed/26846144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.163
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