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14-3-3 Proteins regulate Akt Thr308 phosphorylation in intestinal epithelial cells
Akt activation has been associated with proliferation, differentiation, survival and death of epithelial cells. Phosphorylation of Thr308 of Akt by phosphoinositide-dependent kinase 1 (PDK1) is critical for optimal stimulation of its kinase activity. However, the mechanism(s) regulating this process...
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| Publicat a: | Cell Death Differ |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987727/ https://ncbi.nlm.nih.gov/pubmed/26846144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.163 |
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