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PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

3-phosphoinositide-dependent protein kinase 1 (PDK1), a member of the protein A,G and C (AGC) family of proteins, is a Ser/Thr protein kinase that can phosphorylate and activate other protein kinases from the AGC family, including Akt at Thr308, all of which play important roles in mediating cellula...

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Bibliografiske detaljer
Main Authors: Dangelmaier, Carol, Manne, Bhanu Kanth, Liverani, Elizabetta, Jin, Jianguo, Bray, Paul, Kunapuli, Satya P.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079046/
https://ncbi.nlm.nih.gov/pubmed/24352480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH13-06-0484
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