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G(q)-mediated Akt translocation to the membrane: a novel PIP(3)-independent mechanism in platelets
Akt is an important signaling molecule regulating platelet aggregation. Akt is phosphorylated after translocation to the membrane through G(i) signaling pathways by a phosphatidylinositol-3,4,5-trisphosphate (PIP(3))-dependent mechanism. However, Akt is more robustly phosphorylated by thrombin compa...
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| Опубликовано в: : | Blood |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281826/ https://ncbi.nlm.nih.gov/pubmed/25331114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-576306 |
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