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Low PTEN expression and overexpression of phosphorylated Akt(Ser473) and Akt(Thr308) are associated with poor overall survival in upper tract urothelial carcinoma
The PI3K/Akt signaling pathway serves an essential role in various cellular processes, including cell growth, survival, cell motility, angiogenesis and cell metabolism. Loss of PTEN expression and hyperactivation of Akt can result in tumorigenesis. Previous studies observed expression of the Akt pro...
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| Publicado no: | Oncol Lett |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583738/ https://ncbi.nlm.nih.gov/pubmed/33123258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12210 |
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