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Hypoxia-inducible Factor-dependent Production of Profibrotic Mediators by Hypoxic Hepatocytes
BACKGROUND/AIMS: During the development of liver fibrosis, mediators are produced that stimulate cells in the liver to differentiate into myofibroblasts and to produce collagen. Recent studies demonstrated that the transcription factor, hypoxia-inducible factor-1α (HIF-1α), is critical for upregulat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111079/ https://ncbi.nlm.nih.gov/pubmed/19302442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2009.02015.x |
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