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Hypoxia-inducible Factor-dependent Production of Profibrotic Mediators by Hypoxic Hepatocytes

BACKGROUND/AIMS: During the development of liver fibrosis, mediators are produced that stimulate cells in the liver to differentiate into myofibroblasts and to produce collagen. Recent studies demonstrated that the transcription factor, hypoxia-inducible factor-1α (HIF-1α), is critical for upregulat...

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Bibliografische gegevens
Hoofdauteurs: Copple, Bryan L., Bustamante, Juan J., Welch, Timothy P., Kim, Nam Deuk, Moon, Jeon-OK
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111079/
https://ncbi.nlm.nih.gov/pubmed/19302442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2009.02015.x
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