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Hypoxia-inducible Factor-dependent Production of Profibrotic Mediators by Hypoxic Kupffer Cells
AIM: Liver fibrosis develops when chronic liver injury stimulates cells in the liver to produce mediators that activate hepatic stellate cells and stimulate them to secrete collagen. Recent studies suggest that the hypoxia-regulated transcription factor, hypoxia-inducible factor-1α, is essential for...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886188/ https://ncbi.nlm.nih.gov/pubmed/20412331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2010.00635.x |
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