Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Breast Cancer Latency and Affect Tumor Type

Tissue microenvironment is an important determinant of carcinogenesis. We demonstrate that ionizing radiation, a known carcinogen, affects cancer frequency and characteristics by acting on the microenvironment. Using a mammary chimera model in which an irradiated host is transplanted with oncogenic...

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Main Authors: Nguyen, David H., Oketch-Rabah, Hellen A., Illa-Bochaca, Irineu, Geyer, Felipe C., Reis-Filho, Jorge S., Mao, Jian-Hua, Ravani, Shraddha A., Zavadil, Jiri, Borowsky, Alexander D., Jerry, D. Joseph, Dunphy, Karen A., Seo, Jae Hong, Haslam, Sandra, Medina, Daniel, Barcellos-Hoff, Mary Helen
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110779/
https://ncbi.nlm.nih.gov/pubmed/21575864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.03.011
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