Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Breast Cancer Latency and Affect Tumor Type

Tissue microenvironment is an important determinant of carcinogenesis. We demonstrate that ionizing radiation, a known carcinogen, affects cancer frequency and characteristics by acting on the microenvironment. Using a mammary chimera model in which an irradiated host is transplanted with oncogenic...

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Hoofdauteurs: Nguyen, David H., Oketch-Rabah, Hellen A., Illa-Bochaca, Irineu, Geyer, Felipe C., Reis-Filho, Jorge S., Mao, Jian-Hua, Ravani, Shraddha A., Zavadil, Jiri, Borowsky, Alexander D., Jerry, D. Joseph, Dunphy, Karen A., Seo, Jae Hong, Haslam, Sandra, Medina, Daniel, Barcellos-Hoff, Mary Helen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110779/
https://ncbi.nlm.nih.gov/pubmed/21575864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.03.011
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