Latent Transforming Growth Factor-β Activation in Mammary Gland : Regulation by Ovarian Hormones Affects Ductal and Alveolar Proliferation

Transforming growth factor-β1 (TGF-β1) is a pluripotent cytokine that can inhibit epithelial proliferation and induce apoptosis, but is also widely implicated in breast cancer progression. Understanding its biological action in mammary development is critical for understanding its role in cancer. TG...

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Detalhes bibliográficos
Main Authors: Ewan, Kenneth B., Shyamala, Gopalan, Ravani, Shraddha A., Tang, Yang, Akhurst, Rosemary, Wakefield, Lalage, Barcellos-Hoff, Mary Helen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850834/
https://ncbi.nlm.nih.gov/pubmed/12057913
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