Latent Transforming Growth Factor-β Activation in Mammary Gland : Regulation by Ovarian Hormones Affects Ductal and Alveolar Proliferation

Transforming growth factor-β1 (TGF-β1) is a pluripotent cytokine that can inhibit epithelial proliferation and induce apoptosis, but is also widely implicated in breast cancer progression. Understanding its biological action in mammary development is critical for understanding its role in cancer. TG...

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Hauptverfasser: Ewan, Kenneth B., Shyamala, Gopalan, Ravani, Shraddha A., Tang, Yang, Akhurst, Rosemary, Wakefield, Lalage, Barcellos-Hoff, Mary Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850834/
https://ncbi.nlm.nih.gov/pubmed/12057913
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