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A TGFβ–miR-182-BRCA1 axis controls the mammary differentiation hierarchy

Maintenance of mammary functional capacity during cycles of proliferation and regression depend on appropriate cell fate decisions of mammary progenitor cells to populate an epithelium consisting of secretory luminal cells and contractile myoepithelial cells. It is well established that transforming...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Signal
Hauptverfasser: Martinez-Ruiz, Haydeliz, Illa-Bochaca, Irineu, Omene, Coral, Hanniford, Douglas, Liu, Qi, Hernando, Eva, Barcellos-Hoff, Mary Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619986/
https://ncbi.nlm.nih.gov/pubmed/27923913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf5402
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