BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

BRCA1 deficiency may perturb the differentiation hierarchy present in the normal mammary gland and is associated with the genesis of breast cancers that are genomically unstable and typically display a basal-like transcriptome. Oriented cell division is a mechanism known to regulate cell fates and t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Zhengcheng, Kannan, Nagarajan, Nemirovsky, Oksana, Chen, Helen, Connell, Marisa, Taylor, Brian, Jiang, Jihong, Pilarski, Linda M., Fleisch, Markus C., Niederacher, Dieter, Pujana, Miguel Angel, Eaves, Connie J., Maxwell, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464802/
https://ncbi.nlm.nih.gov/pubmed/28427147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15688
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