BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

BRCA1 deficiency may perturb the differentiation hierarchy present in the normal mammary gland and is associated with the genesis of breast cancers that are genomically unstable and typically display a basal-like transcriptome. Oriented cell division is a mechanism known to regulate cell fates and t...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: He, Zhengcheng, Kannan, Nagarajan, Nemirovsky, Oksana, Chen, Helen, Connell, Marisa, Taylor, Brian, Jiang, Jihong, Pilarski, Linda M., Fleisch, Markus C., Niederacher, Dieter, Pujana, Miguel Angel, Eaves, Connie J., Maxwell, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464802/
https://ncbi.nlm.nih.gov/pubmed/28427147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15688
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