Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2

Construction of a mitotic spindle requires biochemical pathways to assemble spindle microtubules and structural proteins to organize these microtubules into a bipolar array. Through a complex with dynein, the receptor for hyaluronan-mediated motility (RHAMM) cross-links mitotic microtubules to provi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Helen, Mohan, Pooja, Jiang, Jihong, Nemirovsky, Oksana, He, Daniel, Fleisch, Markus C, Niederacher, Dieter, Pilarski, Linda M, Lim, C James, Maxwell, Christopher A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111680/
https://ncbi.nlm.nih.gov/pubmed/24875404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29270
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