The genetic landscape of the childhood cancer medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high density microarrays and sequenced all known protein-coding genes and miRNA genes using Sanger sequencing in a set of 2...

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Detalhes bibliográficos
Main Authors: Parsons, D. Williams, Li, Meng, Zhang, Xiaosong, Jones, Siân, Leary, Rebecca J., Lin, Jimmy Cheng-Ho, Boca, Simina M., Carter, Hannah, Samayoa, Josue, Bettegowda, Chetan, Gallia, Gary L., Jallo, George I., Binder, Zev A., Nikolsky, Yuri, Hartigan, James, Smith, Doug R., Gerhard, Daniela S., Fults, Daniel W., VandenBerg, Scott, Berger, Mitchel S., Marie, Suely Kazue Nagahashi, Shinjo, Sueli Mieko Oba, Clara, Carlos, Phillips, Peter C., Minturn, Jane E., Biegel, Jaclyn A., Judkins, Alexander R., Resnick, Adam C., Storm, Phillip B., Curran, Tom, He, Yiping, Rasheed, B. Ahmed, Friedman, Henry S., Keir, Stephen T., McLendon, Roger, Northcott, Paul A., Taylor, Michael D., Burger, Peter C., Riggins, Gregory J., Karchin, Rachel, Parmigiani, Giovanni, Bigner, Darell D., Yan, Hai, Papadopoulos, Nick, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110744/
https://ncbi.nlm.nih.gov/pubmed/21163964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1198056
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