Doxorubicin loaded iron oxide nanoparticles overcome multidrug resistance in cancer in vitro

Multidrug resistance (MDR) is characterized by the overexpression of ATP-binding cassette (ABC) transporters that actively pump a broad class of hydrophobic chemotherapeutic drugs out of cancer cells. MDR is a major mechanism of treatment resistance in a variety of human tumors, and clinically appli...

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Detalhes bibliográficos
Main Authors: Kievit, Forrest M., Wang, Freddy Y., Fang, Chen, Mok, Hyejung, Wang, Kui, Silber, John R., Ellenbogen, Richard G., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110619/
https://ncbi.nlm.nih.gov/pubmed/21277920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.01.024
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