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Functionalization of iron oxide magnetic nanoparticles with targeting ligands: their physicochemical properties and in vivo behavior

AIMS: To develop and evaluate two tumor-specific nanoprobes by functionalization of a PEG-immobilized nanoparticle with arginine-glycine-aspartic acid (RGD) or chlorotoxin (CTX) ligand that targets α(v)β(3) integrin and MMP-2 receptors, respectively. MATERIALS AND METHODS: The nanoprobes were made o...

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Detalhes bibliográficos
Main Authors: Fang, Chen, Veiseh, Omid, Kievit, Forrest, Bhattarai, Narayan, Wang, Freddy, Stephen, Zach, Li, Chun, Lee, Donghoon, Ellenbogen, Richard G., Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057775/
https://ncbi.nlm.nih.gov/pubmed/21128719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.10.55
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