Nanoparticle-mediated target delivery of TRAIL as gene therapy for glioblastoma

Human tumor necrosis factor α-related apoptosis-inducing ligand (TRAIL) is an attractive cancer therapeutic because of its ability to induce apoptosis in tumor cells while having a negligible effect on normal cells. However, the short serum half-life of TRAIL and lack of efficient in vivo administra...

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Vydáno v:Adv Healthc Mater
Hlavní autoři: Wang, Kui, Kievit, Forrest M., Jeon, Mike, Silber, John R., Ellenbogen, Richard G., Zhang, Miqin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715716/
https://ncbi.nlm.nih.gov/pubmed/26498165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201500563
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