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NT-16 NANOPARTICLE-MEDIATED DELIVERY OF ANTI-Ape1 siRNA SENSITIZES PEDIATRIC BRAIN TUMOR CELLS TO RADIATION THERAPY BY INHIBITING DNA REPAIR

Pediatric brain tumors are the leading cause of death in children, and survival is frequently accompanied by one or more radiation-induced adverse developmental and psychosocial sequelae. Radiotherapy (RT) is an integral component of the treatment for medulloblastoma (MB) and the only effective adju...

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Detalhes bibliográficos
Main Authors: Kievit, Forrest, Stephen, Zachary, Wang, Kui, Dayringer, Christopher, Ellenbogen, Richard, Silber, John, Zhang, Miqin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218424/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou265.15
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