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Doxorubicin loaded iron oxide nanoparticles overcome multidrug resistance in cancer in vitro
Multidrug resistance (MDR) is characterized by the overexpression of ATP-binding cassette (ABC) transporters that actively pump a broad class of hydrophobic chemotherapeutic drugs out of cancer cells. MDR is a major mechanism of treatment resistance in a variety of human tumors, and clinically appli...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110619/ https://ncbi.nlm.nih.gov/pubmed/21277920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.01.024 |
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